DBCO-PEG5-NHS ester
- CAS NO.：1378531-80-6
- Empirical Formula: C36H43N3O11
- Molecular Weight: 693.74
- MDL number: MFCD28334547
- Update Date: 2026-05-28 04:25:39
What is DBCO-PEG5-NHS ester?
Description
DBCO-NHCO-PEG5-NHS ester is a PEG linker containing NHS ester that is able to react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and can also provide a long and flexible connection that minimizes steric hindrance during ligation. DBCO is commonly used for copper-free Click Chemistry reactions.
Properties of DBCO-PEG5-NHS ester
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Acetonitrile (Slightly), Chloroform (Slightly) |
| form | Oil |
| pka | 15.14±0.46(Predicted) |
| color | Yellow to Dark Yellow Sticky |
Safety information for DBCO-PEG5-NHS ester
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DBCO-PEG5-NHS ester
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