CU-CPT-9a
- CAS NO.：2162962-69-6
- Empirical Formula: C16H13NO2
- Molecular Weight: 251.28
- Update Date: 2026-05-28 04:59:38
What is CU-CPT-9a?
Description
CU-CPT9b is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM). It inhibits activation of NF-ĸB induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.
The Uses of CU-CPT-9a
CU-CPT9a is a potent TLR8 inhibitor (IC50 = 0.5 nM and Kd = 21 nM). Stabilizes the TLR8 dimer in its resting state, preventing activation. Suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells.
Properties of CU-CPT-9a
| Boiling point: | 452.6±45.0 °C(Predicted) |
| Density | 1.287±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml |
| form | A crystalline solid |
| pka | 8.46±0.20(Predicted) |
| color | White to yellow |
Safety information for CU-CPT-9a
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for CU-CPT-9a
New Products
1,3-Dichloroacetone Ethylene Ketal 1-N-Boc-3-(aminoethyl)azetidine 4-N-BOC-AMINO-4-CARBOXYTETRAHYDROPYRAN AMino-(3-Methylphenyl)-acetic acid 3-AMINO-3-(2-CHLORO-PHENYL)-PROPIONIC ACID 4-Fluorophenylglycine 4, 4'-Ditolylamine (or) 4,4-Dimethyl Diphenylamine 2-Bromo-5-Chloropyridine 2-Picolinic acid N-oxide 4-Butyl Resorcinol 2-(2,4-Diaminophenoxy)ethanol Dihydrochloride 5-Bromo-2-Hydroxy-3-Nitro Pyridine 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile Tetracaine Hydrochloride Ep Grade 2,2,2-Trichloroethyl chloroformate 5-Bromo-4-chloro-3-indolyl-β-D-galactopyranoside 4-Pentyn-1-ol 2-Bromo-6-fluoroaniline 5-fluoro-1,3-benzodioxole 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole 2-(Chloromethyl) quinazolin-4(3H)-one 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinolineRelated products of tetrahydrofuran
You may like
-
944401-57-4 98+View Details
944401-57-4 -
1,3-Dichloroacetone Ethylene Ketal 26271-50-1 98+View Details
26271-50-1 -
68208-20-8 3-AMINO-3-(2-CHLORO-PHENYL)-PROPIONIC ACID 98+View Details
68208-20-8 -
7292-73-1 98+View Details
7292-73-1 -
68208-20-8 3-AMINO-3-(2-CHLORO-PHENYL)-PROPIONIC ACID 98+View Details
68208-20-8 -
7292-73-1 98+View Details
7292-73-1 -
68208-20-8 3-AMINO-3-(2-CHLORO-PHENYL)-PROPIONIC ACID 98+View Details
68208-20-8 -
7292-73-1 98+View Details
7292-73-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.