4-(7-methoxyquinolin-4-yl)-2-methylphenol

CAS NO.：2165340-32-7
Empirical Formula: C17H15NO2
Molecular Weight: 265.31
MDL number: MFCD31689252
Update Date: 2026-05-28 05:17:19

What is 4-(7-methoxyquinolin-4-yl)-2-methylphenol?

The Uses of 4-(7-methoxyquinolin-4-yl)-2-methylphenol

CU-CPT9a is a potent TLR8 inhibitor (IC50 = 0.5 nM and Kd = 21 nM). Stabilizes the TLR8 dimer in its resting state, preventing activation. Suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells.

Storage

Store at -20°C

Properties of 4-(7-methoxyquinolin-4-yl)-2-methylphenol

Boiling point:	429.7±45.0 °C(Predicted)
Density	1.201±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml
form	A crystalline solid
pka	8.47±0.20(Predicted)
color	Light yellow to yellow

Safety information for 4-(7-methoxyquinolin-4-yl)-2-methylphenol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.