CPPG
Synonym(s):(R,S)-α-Cyclopropyl-4-phosphonophenylglycine
- CAS NO.：183364-82-1
- Empirical Formula: C11H14NO5P
- Molecular Weight: 271.21
- MDL number: MFCD00673967
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-17 18:22:24
What is CPPG?
The Uses of CPPG
(RS)-CPPG is the most potent group II/III mGluR antagonist.
What are the applications of Application
(RS)-CPPG is the most potent group II/III mGluR antagonist
Definition
ChEBI: 2-amino-2-cyclopropyl-2-(4-phosphonophenyl)acetic acid is an alpha-amino acid.
Biological Activity
Potent group II/III mGlu receptor antagonist, with approximately 20-fold selectivity for group III over group II (IC 50 values of 2.2 and 46.2 nM respectively). A much less potent antagonist at group I receptors in neonatal rat cortical slices (K b = 0.65 ± 0.07 nM). Also available as part of the Group III mGlu Receptor Tocriset™ .
Storage
Room temperature
Properties of CPPG
| storage temp. | Store at RT |
| solubility | H2O: >5mg/mL |
| form | Solid |
| color | white to beige |
Safety information for CPPG
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for CPPG
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