Coelenterazine hcp
Synonym(s):CLZN-hcp
- CAS NO.：123437-32-1
- Empirical Formula: C25H25N3O2
- Molecular Weight: 399.48
- MDL number: MFCD03453204
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:12:54
What is Coelenterazine hcp?
The Uses of Coelenterazine hcp
Coelenterazine hcp has been used:
- as a component of coelenterazine reagent in the reporter assay
- in the purification of Renilla luciferase-labeled Annexin V
- in evaluating the activity of aequorin in Escherichia coli
General Description
Coelenterazine hcp is a semisynthetic analog of coelenterazine.
Biochem/physiol Actions
Coelenterazine hcp has 190 times higher luminescence intensity than native coelenterazine and a faster response time than native coelenterazine.
Properties of Coelenterazine hcp
| Melting point: | >200℃ |
| storage temp. | -20°C |
| solubility | Soluble in ethanol, methanol |
| form | solid |
| color | Yellow |
| λmax | 433nm |
| Biological Applications | Calcium indicator; assaying luminescent enzyme; measuring luciferase activity; as a substrate for luciferase; screening HIV-1 protease inhibitors; bioluminescence resonance energy transfer (BRET) detection system |
Safety information for Coelenterazine hcp
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Coelenterazine hcp
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