CIS-ACONITIC ANHYDRIDE
Synonym(s):cis-Propene-1,2,3-tricarboxylic anhydride
- CAS NO.：6318-55-4
- Empirical Formula: C6H4O5
- Molecular Weight: 156.09
- MDL number: MFCD00005524
- EINECS: 228-663-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:25:34
What is CIS-ACONITIC ANHYDRIDE?
The Uses of CIS-ACONITIC ANHYDRIDE
cis-Aconitic anhydride is used in the preparation of poly(amino acid)-containing copolymers with gradient pH-sensitive side groups initiated by the amino groups in methoxy poly(ethylene glycol)-block-poly(L-lysine). It is also involved in the preparation of pH-sensitive anti-tumor prodrug nanoparticles by conjugation with D-alfa-tocopheryl polyethylene glycol 1000 succinate (TPGS).
Purification Methods
Reflux it in xylene (7.5 parts) for 1hour, then evaporate and recrystallise the residue from *C6H6. Alternatively, reflux it in Ac2O, evaporate and recrystallise from *C6H6. It is sensitive to moisture. [IR: Groth & Dahlén Acta Chem Scand 21 291 1967, Malachowski & Maslowski Chem Ber 61 2523 1928, NMR: Gawron & Mahajan Biochemistry 5 2335 1966.] [Beilstein 18/8 V 530.]
Properties of CIS-ACONITIC ANHYDRIDE
| Melting point: | 75-78 °C (lit.) |
| Boiling point: | 397.8±25.0 °C(Predicted) |
| Density | 1.621±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 3?+-.0.10(Predicted) |
| Sensitive | Moisture Sensitive |
| BRN | 127575 |
| CAS DataBase Reference | 6318-55-4(CAS DataBase Reference) |
| EPA Substance Registry System | 3-Furanacetic acid, 2,5-dihydro-2,5-dioxo- (6318-55-4) |
Safety information for CIS-ACONITIC ANHYDRIDE
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for CIS-ACONITIC ANHYDRIDE
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline 5-Hydroxy-3,9-dimethyl-7H-benzo[c]fluoren-7-one Methyl 4-(acetyloxy)-6-methoxy-1-(4-methoxyphenyl)-2naphthalenecarboxylate 4-Hydroxy-6,7-dimethoxy-1-phenyl-2naphthalenecarboxylic acid (3,5-Dibromophenyl)[4-(trifluoromethyl)phenyl]methanone (4-butoxyphenyl)(4-fluorophenyl)methanone (4-Bromophenyl)(3,4-dimethoxyphenyl)methanone Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity Benzyl-N,4-dimethylpiperidine-3- amine dihydrochloride 3-(4-phenoxyphenyl)-1H- pyrazolo[3,4- d]pyrimidin-4- amine 4-Ethyl-4-hydroxy-1,4,7,8-tetrahydro-3H,10H-spiro[pyrano[3,4-f]indolizine-6,2'-[1,3]dioxolane]-3,10-dione (E)-N'-(2-cyano-4-nitrophenyl)- N,N-dimethylformimidamide N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide 5-bromopyridin-2-amine 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy BenzylcyanideRelated products of tetrahydrofuran
You may like
-
6318-55-4 cis-Aconitic acid anhydride 98%View Details
6318-55-4 -
cis-Aconitic anhydride CAS 6318-55-4View Details
6318-55-4 -
151239-47-3 98+View Details
151239-47-3 -
4-Hydroxy-6-methyl-1-(4-methylphenyl)-2naphthalenecarboxylic acid 98+View Details
101894-09-1 -
83883-25-4 98+View Details
83883-25-4 -
(3,5-dibromophenyl)(4-methoxyphenyl)methanone 1991533-97-1 98+View Details
1991533-97-1 -
54598-15-1 4,5,7-Trimethyl-2(1H)-quinolinone 98+View Details
54598-15-1 -
4-(6-HYDROXYHEXYLOXY)BENZOIC ACID 83883-25-4 98+View Details
83883-25-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.