Chloro[(tri-tert-butylphosphine)-2-(2-aMinobiphenyl)]palladiuM(II)

Synonym(s):Chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)] palladium(II)

CAS NO.：1375325-71-5
Empirical Formula: C24H37ClNPPd
Molecular Weight: 512.41
MDL number: MFCD21608496
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 04:51:46

Chloro[(tri-tert-butylphosphine)-2-(2-aMinobiphenyl)]palladiuM(II) Structural

What is Chloro[(tri-tert-butylphosphine)-2-(2-aMinobiphenyl)]palladiuM(II)?

The Uses of Chloro[(tri-tert-butylphosphine)-2-(2-aMinobiphenyl)]palladiuM(II)

P(t-Bu)₃ Pd G2 (Chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)] palladium(II), Pd/P(t-Bu)₃) may be used as catalyst in the following studies:

Synthesis of sterically hindered biaryls (tetra-ortho-substituted), via cross-coupling reactions of aryl chlorides.
Stille cross-couplings reactions of aryl chloride.
Synthesis of chloropeptin I, via Stille cross-coupling reaction.
Heck reaction.
Negishi cross-coupling reactions.

What are the applications of Application

Catalyst for the Suzuki Coupling of brominated 2,1-borazaronaphthalenes and potassium organotrifluoroborates.

General Description

P(t-Bu)₃ Pd G2 (Chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)] palladium(II)) is a second generation (G2) precatalyst containing a biphenyl-based ligand. Product participates in various palladium catalyzed cross-coupling reactions, C-C, C-N and C-O bond formation reactions, and Suzuki-Miyaura coupling reactions. It generates active Pd catalyst at room temperature in the presence of weak phosphate or carbonate bases. It has been proposed as an active catalyst for use in Stille reactions of aryl halides (bromides and chlorides).

Properties of Chloro[(tri-tert-butylphosphine)-2-(2-aMinobiphenyl)]palladiuM(II)

Melting point:	158-160°C
form	Powder
color	yellow
InChI	InChI=1S/C12H9N.C12H27P.ClH.Pd/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-10(2,3)13(11(4,5)6)12(7,8)9;;/h1-6,8-9,13H;1-9H3;1H;/q-2;;;+2

Safety information for Chloro[(tri-tert-butylphosphine)-2-(2-aMinobiphenyl)]palladiuM(II)

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for Chloro[(tri-tert-butylphosphine)-2-(2-aMinobiphenyl)]palladiuM(II)

InChIKey	CCFGXRYKSYUWKT-UHFFFAOYSA-N
SMILES	P([Pd+2]1(NC2=CC=CC=C2C2=CC=CC=[C-]12)[Cl-])(C(C)(C)C)(C(C)(C)C)C(C)(C)C

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