(Chloromethylene)dimethyliminium chloride
Synonym(s):(Chlormethylene)dimethylammonium chloride;Arnold′s reagent;Dimethylchloroformiminium chloride;Vilsmeier reagent
- CAS NO.：3724-43-4
- Empirical Formula: C3H7ClN.Cl
- Molecular Weight: 128
- MDL number: MFCD00011868
- EINECS: 425-970-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:12:30
What is (Chloromethylene)dimethyliminium chloride?
Chemical properties
Pale brown to yellowish-brown crystalline powder
The Uses of (Chloromethylene)dimethyliminium chloride
(Chloromethylene)dimethylammonium chloride is used in the synthesis of beta-lactams, n-vinyl substituted indoles and fused 2-pyridone rings and 2-azetidinones. It is used as a formylating agent and used in the preparation of anti-poxvirus agents. It is used in Staudinger reaction and Hundsdiecker-barton iododecarboxylation reaction. It is widely used for studying organic photosensitizers, which finds application in dye-sensitized solar cells.
The Uses of (Chloromethylene)dimethyliminium chloride
Reagent or Reactant for the synthesis of:
- β-Lactams vis the Staudinger reaction
- N-vinyl substituted indoles via cross coupling of NH-indoles with vinyl bromides
- Multi ring-fused 2-pyridone-based fluorescent scaffold
- ester prodrugs as anti-poxvirus agents
- Trimethine cyanine dyes for sensing G-quadruplex formation
- Phospha-isosteres via Hundsdiecker-Barton iododecacarboxylation
- 2-Azetidinones via [2+2]-cycloaddition
Used for studying organic photosensitizers for application in dye-sensitized solar cells
What are the applications of Application
(Chloromethylene)dimethyliminium chloride is a reagent employed in the preparation of β-lactams
Properties of (Chloromethylene)dimethyliminium chloride
| Melting point: | 132 °C (dec.) (lit.) |
| Boiling point: | 204.27°C (rough estimate) |
| Density | 1.3578 (rough estimate) |
| refractive index | 1.4525 (estimate) |
| storage temp. | 2-8°C |
| form | Crystalline Powder |
| color | Pale brown to yellow-brown |
| Water Solubility | reacts |
| Sensitive | Moisture Sensitive |
| BRN | 3566322 |
| CAS DataBase Reference | 3724-43-4(CAS DataBase Reference) |
| EPA Substance Registry System | Methanaminium, N-(chloromethylene)-N-methyl-, chloride (3724-43-4) |
Safety information for (Chloromethylene)dimethyliminium chloride
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (Chloromethylene)dimethyliminium chloride
(Chloromethylene)dimethyliminium chloride manufacturer
DR ACHARYA LABORATORIES PVT LTD
1Y
Phone:+91-9820308443
Whatsapp: +91-9820308443
product: Vilsmeier reagent OR (Chloromethylene)dimethyliminium chloride 3724-43-4 98%
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