CARDIN

Originator

Vibeline ,Bellon ,France,1960

The Uses of CARDIN

Visnadine is used as a coumarin scaffold for anti-inflammatory drug development, melanin biosynthetic inhibitory activity, anticellulite efficacy in female patient with cellulite blemish affected by fat accumulation or new anticellulite treatment.

Definition

ChEBI: Visnadin is a member of coumarins.

Manufacturing Process

Ammi visnaga is a plant of the Umbelliferae family, which has been known and used for its therapeutic properties by the peoples of the Mediterranean basin since time immemorial.
Visnadine may be extracted from the umbels of Ammi visnaga by an organic solvent having a boiling point less than 110°C. The resulting solution is concentrated first by heating in a water bath and then is allowed to stand some time at a temperature of about 20°C and if necessary is treated for separation of gummy constituents therefrom, after which the solution is concentrated under reduced pressure. Finally, the crude product is crystallized and separated by retaining it on a filter.
This crude product may then, according to the process, be purified by mixing it with petroleum ether and allowing it to stand at ordinary temperature, then filtering it to obtain the pure visnadine.

Therapeutic Function

Coronary vasodilator, Antiarrhythmic