CarbaMic acid,[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-, 1,1-diMethylethyl ester (9CI)

CAS NO.：506427-91-4
Empirical Formula: C23H35Cl2N3O2
Molecular Weight: 456.45
MDL number: MFCD28386599
Update Date: 2026-05-28 04:46:17

What is CarbaMic acid,[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-, 1,1-diMethylethyl ester (9CI)?

The Uses of CarbaMic acid,[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-, 1,1-diMethylethyl ester (9CI)

tert-Butyl ((1R,4R)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)carbamate is an intermediate for the synthesis of Desmethyl Cariprazine Hydrochloride (D291365), a derivative of Cariprazine (C183490) which is an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.

Properties of CarbaMic acid,[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-, 1,1-diMethylethyl ester (9CI)

Boiling point:	570.2±50.0 °C(Predicted)
Density	1.21±0.1 g/cm3(Predicted)
pka	12.61±0.40(Predicted)

Safety information for CarbaMic acid,[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-, 1,1-diMethylethyl ester (9CI)

Computed Descriptors for CarbaMic acid,[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-, 1,1-diMethylethyl ester (9CI)

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