Caftaric acid
Synonym(s):2-Caffeoyl-L -tartaric acid
- CAS NO.：67879-58-7
- Empirical Formula: C13H12O9
- Molecular Weight: 312.23
- MDL number: MFCD02094177
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-11-04 17:01:53
What is Caftaric acid?
Description
Caftaric acid is a phenolic acid and a tartaric acid ester form of caffeic acid . It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) free radicals in a cell-free assay (EC50 = 20.4 μM) and inhibits oxidation of LDL isolated from human plasma by 97.6% compared to vehicle control in vitro when used at a concentration of 5 μM. Caftaric acid is the main phenolic compound in V. vinifera white, pink, and black table grapes as well as various wines. In vivo, caftaric acid content in dietary-administered red wine positively correlates with inhibition of protein carbonylation and decreased superoxide dismutase (SOD), glutathione peroxidase (Gpx), and catalase activities in mice.
The Uses of Caftaric acid
Caftaric Acid is used in cancer therapy as an anticancer drug. Affecting the up regulation or down regulation of drug transporters or cytochrome p450 enzymes. Also provides antioxidant effects, found in wines.
Definition
ChEBI: Caftaric acid is a hydroxycinnamic acid.
Properties of Caftaric acid
| Melting point: | 124～125℃ |
| Boiling point: | 618.2±55.0 °C(Predicted) |
| Density | 1.694±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Methanol (Slightly), Water (Slightly, Heated, Sonicated) |
| form | neat |
| pka | 2.18±0.25(Predicted) |
| form | Solid |
| color | White to Pale Beige |
| Odor | at 100.00?%. odorless |
| Stability: | Hygroscopic |
Safety information for Caftaric acid
Computed Descriptors for Caftaric acid
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