Butanilicaine hydrochloride
- CAS NO.：3785-21-5
- Empirical Formula: C13H19ClN2O
- Molecular Weight: 254.76
- MDL number: MFCD00864434
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is Butanilicaine hydrochloride?
Originator
Butanilicaine,Enreco, INC
The Uses of Butanilicaine hydrochloride
Butanilicaine Hydrochloride, is a local anesthetic.
Definition
ChEBI: An amino acid amide amide in which N-butylglycine and 2-chloro-6-methylaniline have combined to form the amide bond; used as a local anaesthetic (amide caine).
Manufacturing Process
To a solution of 4-bromo-2-methylaniline is added 13 g of chloroacetyl
chloride. After the reaction is finished to the mixture id added a solution of 33
g sodium acetate in 138 ml of water. Chloroacetic acid 4-bromo-2-
methylanilide is filtered; yield 24 g, M.P. 135°C (crystallization from ethanol).
20 g of chloroacetic acid 4-bromo-2-methylanilide is dissolved in 200 ml of butylamine. After about 15 hours to the solution is added 2 N hydrochloric
acid. Butylaminoacetic acid 4-bromo-2-methylanilide hydrochloride is removed
by suction and washed with water; yield 90%, M.P. 252-253°C (from
methanol).
Therapeutic Function
Local anesthetic
Properties of Butanilicaine hydrochloride
| Melting point: | 45-46° |
| Boiling point: | bp0.001 145°; bp0.5 166-167° |
| Density | 1.129±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 13.41±0.70(Predicted) |
| color | Pale Brown to Light Brown |
| NIST Chemistry Reference | Butanilicaine(3785-21-5) |
Safety information for Butanilicaine hydrochloride
Computed Descriptors for Butanilicaine hydrochloride
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amineRelated products of tetrahydrofuran
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