Brodimoprim
- CAS NO.：56518-41-3
- Empirical Formula: C13H15BrN4O2
- Molecular Weight: 339.1878
- MDL number: MFCD00864849
- EINECS: 2602388
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-29 15:43:00
What is Brodimoprim?
Description
Brodimoprim, a dihydrofolate reductase inhibitor, was introduced for the treatment of common infections of upper respiratory tract such as sinusitis and exacerbation of chronic bronchitis. It has a broad spectrum of antimicrobial activities against most Gram-positive and -negative pathogens including some bacterial strains that are resistant to amoxicillin, a widely used antibiotic for the indicated infections. Brodimoprim also has a favorable pharmacokinetic profile exemplified by its long half-life and good tissue penetration.
Chemical properties
Off-White to Pale Yellow Solid
Originator
Helsinn (Switzerland)
The Uses of Brodimoprim
A structural derivative of Trimethoprim (T795615). A selective dihydrofolate reductase inhibitor; diaminopyridine antibacterial agent.
Definition
ChEBI: An aminopyrimidine that is 2,4-diaminopyrimidine in which the hydrogen at position 5 has been replaced by a 4-bromo-3,5-dimethoxybenzyl group.
brand name
Hyprim;Unitrim
Properties of Brodimoprim
| Melting point: | 225-228° |
| storage temp. | Amber Vial, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Sparingly) |
| form | Solid |
| pka | 7.15(at 25℃) |
| color | White to Pale Yellow |
| Stability: | Light Sensitive |
Safety information for Brodimoprim
Computed Descriptors for Brodimoprim
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 2-Bromo-5-Iodopyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 2-Hydroxy-5-methoxybenzoic acid 2-Cyanopyrimidine Xanthene-9-carboxylic acid 4,4-Diethoxybutanenitrile Methyl 4-amino-2,3-difluoro-5-nitrobenzoate 5-fluoro-1,3-benzodioxole 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole 4-Chloro-2-methyl quinoline 2-Amino-4-phenyl-thiazole 2-(Chloromethyl) quinazolin-4(3H)-oneRelated products of tetrahydrofuran
You may like
-
2-Bromo-4-nitropyridine-N-oxide 52092-43-0 98%View Details
52092-43-0 -
18979-61-8 98%View Details
18979-61-8 -
4, 4'-Ditolylamine (or) 4,4-Dimethyl Diphenylamine 620-93-9 98%View Details
620-93-9 -
2-Bromo-5-Chloropyridine 98%View Details
40473-01-6 -
2-Picolinic acid N-oxide 824-40-8 98%View Details
824-40-8 -
15862-34-7 5-Bromo-2-Hydroxy-3-Nitro Pyridine 98%View Details
15862-34-7 -
2-(2,4-Diaminophenoxy)ethanol Dihydrochloride 98%View Details
66422-95-5 -
Eperisone Hydrochloride APIView Details
56839-43-1