Uridine 5'-monophosphate
Synonym(s):U 5′-P;UMP;Uridylic acid
- CAS NO.:58-97-9
- Empirical Formula: C9H13N2O9P
- Molecular Weight: 324.18
- MDL number: MFCD00067346
- EINECS: 200-408-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-05 14:33:18
What is Uridine 5'-monophosphate?
Description
Uridine 5'-monophosphateis a nucleotide that is synthesized from uridine. Uridine 5'-monophosphate has been shown to have anticancer activity in vitro and in vivo, as well as antiviral activity against herpes viruses. It is also used in foods such as infant formula to as a method of increasing uridine levels in blood.
Chemical properties
(Uridine-3′-phosphate) Crystallizes in prisms from methanol. Freely soluble in water and alcohol; dextrorotatory in solution.
The Uses of Uridine 5'-monophosphate
Biochemical research.
The Uses of Uridine 5'-monophosphate
Uridine 5''-Monophosphate is a nucleotide used as monomer in RNA. It is used in foods such as infant formula to as a method of increasing uridine levels in blood.
Definition
The monophosphoric ester of uracil, i.e., the nucleotide containing uracil-d-ribose and phosphoric acid. The phosphate may be esterified to either the 2, 3, or 5 carbon of ribose, yielding uridine-2′-phosphate, uridine-3′phosphate, and uridine-5′-phosphate, respectively.
General Description
Uridine 5′-monophosphate acts as a precursor for all pyrimidine nucleotides.
Properties of Uridine 5'-monophosphate
| Melting point: | 202°C (rough estimate) |
| Density | 1.865±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | H2O: soluble50mg/mL, clear, colorless |
| form | solid |
| pka | pK1:6.63 (25°C) |
| color | White to Off-White |
| InChI | InChI=1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 |
| CAS DataBase Reference | 58-97-9 |
| EPA Substance Registry System | 5'-Uridylic acid (58-97-9) |
Safety information for Uridine 5'-monophosphate
Computed Descriptors for Uridine 5'-monophosphate
| InChIKey | DJJCXFVJDGTHFX-XVFCMESISA-N |
| SMILES | P(OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](O)[C@@H]1O)(O)(O)=O |
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