Boc-Lys(Ac)-AMC
Synonym(s):Boc-Lys(Ac)-AMC, MAL, N-(4-Methyl-7-coumarinyl)-N α-(t-butoxycarbonyl)-N ω-acetyllysinamide;Histone Deacetylase Substrate, Fluorogenic - CAS 233691-67-3 - Calbiochem
- CAS NO.：233691-67-3
- Empirical Formula: C23H31N3O6
- Molecular Weight: 445.51
- MDL number: MFCD02683946
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:49:10
What is Boc-Lys(Ac)-AMC?
Description
Boc-Lys(Ac)-AMC is a fluorescent substrate for histone deacetylases (HDACs). Following deacetylation by an HDAC, Boc-Lys-AMC is cleaved by trypsin and 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify HDAC activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
Properties of Boc-Lys(Ac)-AMC
| Boiling point: | 732.6±60.0 °C(Predicted) |
| Density | 1.209±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 3 mg/ml |
| form | White crystalline solid |
| pka | 11.23±0.46(Predicted) |
| color | White to off-white |
Safety information for Boc-Lys(Ac)-AMC
Computed Descriptors for Boc-Lys(Ac)-AMC
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