Bis(4-hydroxycinnamoyl)methane
Synonym(s):1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
- CAS NO.:24939-16-0
- Empirical Formula: C19H16O4
- Molecular Weight: 308.33
- MDL number: MFCD03419284
- EINECS: 607-464-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:54:00
What is Bis(4-hydroxycinnamoyl)methane?
The Uses of Bis(4-hydroxycinnamoyl)methane
Bisdemethoxycurcumin is one of the three major forms of curcuminoids found in the rhizomes of turmeric. Bisdemethoxycurcumin displays antioxidant, anti-inflammatory as well as chemotherapeutic activity. Bisdemethoxycurcumin acts as an inhibitor of human pancreatic a-amylase, a target for type-2 diabetes .
Definition
ChEBI: Bisdemethoxycurcumin is a beta-diketone that is methane in which two of the hydrogens are substituted by 4-hydroxycinnamoyl groups. It has a role as a metabolite and an EC 3.2.1.1 (alpha-amylase) inhibitor. It is a beta-diketone, a polyphenol, an enone and a diarylheptanoid. It is functionally related to a 4-coumaric acid.
Properties of Bis(4-hydroxycinnamoyl)methane
| Melting point: | 91-93℃ |
| Boiling point: | 551.3±45.0 °C(Predicted) |
| Density | 1.285 |
| storage temp. | 2-8°C |
| solubility | DMSO: ≥20mg/mL |
| form | neat |
| pka | 8.67±0.46(Predicted) |
| form | Solid |
| color | Light yellow to Brown |
| Stability: | Light Sensitive |
Safety information for Bis(4-hydroxycinnamoyl)methane
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for Bis(4-hydroxycinnamoyl)methane
| InChIKey | PREBVFJICNPEKM-YDWXAUTNSA-N |
Bis(4-hydroxycinnamoyl)methane manufacturer
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![CURCUMIN, [3H]-](https://img.chemicalbook.in/StructureFile/ChemBookStructure9/GIF/CB0304045.gif)

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