Bam (8-22)
Synonym(s):BAM (8-22) trifluoroacetate salt;Bovine Adrenal Medulla 8-22 trifluoroacetate salt;Bovine adrenal medulla peptide (8-22) trifluoroacetate salt;L-Valyl-glycyl-L-arginyl-L-prolyl-L-α-glutamyl-L-tryptophyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-arginyl-L-tyrosyl-glycine trifluoroacetate salt;Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly trifluoroacetate salt
- CAS NO.：412961-36-5
- Empirical Formula: C91H127N25O23S
- Molecular Weight: 1971.20078
- MDL number: MFCD04974822
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:53:17
What is Bam (8-22)?
The Uses of Bam (8-22)
BAM8-22 trifluoroacetate salt has been used in the study to identify the functions of Mas-related gene (Mrg) C in the pathogenesis and treatment of bone cancer pain (BCP).
Biochem/physiol Actions
BAM8-22 is a selective agonist for the sensory neuron specific G-protein coupled receptors (SNSRs). BAM8-22 inhibits development of morphine tolerance in rats. BAM8-22 is inactive at opioid receptors. Also, BAM8–22 is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1. BAM8-22 produces itch and nociceptive sensations in humans in a histamine-independent manner.
Storage
-20°C (desiccate)
Properties of Bam (8-22)
| storage temp. | Desiccate at -20°C |
| form | powder |
| color | white to off-white |
| Water Solubility | Soluble to 1 mg/ml in water |
Safety information for Bam (8-22)
Computed Descriptors for Bam (8-22)
New Products
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