Balsalazide sodium hydrate
- CAS NO.：150399-21-6
- Empirical Formula: C17H18N3NaO7
- Molecular Weight: 399.33
- MDL number: MFCD01631117
- EINECS: 1533716-785-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is Balsalazide sodium hydrate?
The Uses of Balsalazide sodium hydrate
Balsalazide Disodium Dihydrate is an analogue of Sulfasalazine (S699084), A prodrug of 5-aminosalicylic acid where carrier molecule is 4-aminobenzoyl-β-alanine. Anti-inflammatory (gastrointestinal).
The Uses of Balsalazide sodium hydrate
antiinflammatory
Definition
ChEBI: The dihydrate of the disodium salt of balsalazide. A prodrug, releasing the anti-inflammatory 5-aminosalicylic acid (mesalazine) in the large intestine, it is used in the treatment of ulcerative colitis.
Indications
Balsalazide disodium is delivered intact to the colon, where it is cleaved by bacterial azoreduction to release equimolar quantities of mesalamine, the therapeutically active portion of the molecule, and 4-aminobenzoyl-β-alanine; the latter compound is only minimally absorbed and is largely inert.
brand name
Colazal (Salix).
Properties of Balsalazide sodium hydrate
| Melting point: | >195°C (dec.) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | Yellow |
| Merck | 14,945 |
Safety information for Balsalazide sodium hydrate
Computed Descriptors for Balsalazide sodium hydrate
| InChIKey | XDCNKOBSQURQOZ-MVIJUDHYSA-L |
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