ATRACTYLOSIDE SODIUM SALT
- CAS NO.：100938-11-2
- Empirical Formula: C30H44Na2O16S2
- Molecular Weight: 770.77
- MDL number: MFCD00171231
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 15:13:25
What is ATRACTYLOSIDE SODIUM SALT?
Chemical properties
ATRACTYLOSIDE SODIUM SALT is White Solid
The Uses of ATRACTYLOSIDE SODIUM SALT
A specific inhibitor of the adenine nucleotide translocase (ANT), which is a mitochondrial ADP/ATP carrier. It is also a proapoptotic ligand of ANT that induces pore formation by ANT, and results in p ermeabilization of the mitochondria membrane. Studies on rat hearts suggest that Atractyloside inhibits chloride channels from the mitochondrial membrane. It is used to probe the source of procaspase 8 in human fibroblasts and mouse clonal striatal cells, as related to death receptor-mediated apoptosis. ATRACTYLOSIDE SODIUM SALT induces the release of ahyaluronidase-induced murine WW domain-containing oxidore ductase from cultured COS-7 cells, with respect to tumor necrosis factor cytotoxicity.
Safety information for ATRACTYLOSIDE SODIUM SALT
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