apratastat
Synonym(s):(3S)-N-Hydroxy-4-[[4-[(4-hydroxy-2-butyn-1-yl)oxy]phenyl]sulfonyl]-2,2-dimethyl-3-thiomorpholinecarboxamide;(3S)-N-Hydroxy-4-[[4-[(4-hydroxy-2-butynyl)oxy]phenyl]sulfonyl]-2,2-dimethyl-3-thiomorpholinecarboxamide;TMI 005;TMI-005
- CAS NO.：287405-51-0
- Empirical Formula: C17H22N2O6S2
- Molecular Weight: 414.5
- MDL number: MFCD13152357
- Update Date: 2026-05-28 04:23:04
What is apratastat?
The Uses of apratastat
Treatment of rheumatoid arthritis.
Definition
ChEBI: Apratastat is a sulfonamide.
brand name
(Wyeth).
Properties of apratastat
| Density | 1.390 |
| storage temp. | Store at -20°C |
| solubility | DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:40): 0.02 mg/ml; Ethanol: 10 mg/ml |
| form | A crystalline solid |
| pka | 9.25±0.23(Predicted) |
| color | White to off-white |
Safety information for apratastat
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for apratastat
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