Amicetin-A
- CAS NO.：17650-86-1
- Empirical Formula: C29H42N6O9
- Molecular Weight: 618.68
- MDL number: MFCD01674585
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-18 09:51:14
What is Amicetin-A?
Enzyme inhibitor
These pyrimidine-containing glycoside antibiotic (FWAmicetin-A = 617.69 g/mol (free base); CAS 17650-86-1; FWAmicetin-B = 532.59 g/mol (free base)) from Streptomyces vinaceus-drappus and S. fasciculatus inhibits protein biosynthesis, exerting its bacteriostatic most potently on Grampositive bacteria. Amicetin B, also called plicacetin, was isolated from Streptomyces plicatus and has the identical structure minus the amethylseryl residue. It is weaker in action compared to amicetin A. Target(s): peptidyltransferase; peptidyl-tRNA hydrolase, or aminoacyl-tRNA hydrolase; ribonuclease P; protein biosynthesis.
Properties of Amicetin-A
| Melting point: | 244-245° |
| Boiling point: | 660.6°C (rough estimate) |
| alpha | D24 +116.5° (c = 0.5 in 0.1N HCl) |
| Density | 1.2721 (rough estimate) |
| refractive index | 1.6400 (estimate) |
| pka | pKa = 10.4, 7.0(at 25℃) |
Safety information for Amicetin-A
Computed Descriptors for Amicetin-A
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