Alexidine dihydrochloride
Synonym(s):1,1′-Hexamethylene-bis(5-[2-ethylhexyl]biguanide)
- CAS NO.：22573-93-9
- Empirical Formula: C26H56N10
- Molecular Weight: 508.79
- MDL number: MFCD00082369
- EINECS: 245-096-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:55:49
What is Alexidine dihydrochloride?
Chemical properties
White Powder with Light Yellow Cast
Originator
Alexidine ,Science Lab.
The Uses of Alexidine dihydrochloride
Alexidine Dihydrochloride has antibacterial, antiplaque properties against Streptococcus mutans, Actinomyces ciscosus, and Actinomyces naesludii.
Definition
ChEBI: An amphipathic bisbiguanide with a structure consisting of two (2-ethylhexyl)guanide units linked by a hexamethylene bridge.
Manufacturing Process
A mixture of 16 g (0.09 mole) 1,1'-hexamethylene-bis(3-cyanoguanidine) and 20 d (0.12 mole) 2-ethylhexylamine hydrochloride is heated at 150-155°C for 3 hours. The mixture is cooled and the product is dissolved in 75 ml of hot water. The solution is treated with activated charcoal. 1,1'-Hexamethylene-bis- (5-(ethylhexyl)biguanide) is recrystalluized from methanol-ether, melting point 220.6-223.4°C.
Therapeutic Function
Antiseptic
Properties of Alexidine dihydrochloride
| Melting point: | 220-224 |
| Boiling point: | 574.5±60.0 °C(Predicted) |
| Density | 1.10±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Methanol (Slightly) |
| form | Solid |
| pka | 12.34±0.10(Predicted) |
| color | White to Off-White |
Safety information for Alexidine dihydrochloride
Computed Descriptors for Alexidine dihydrochloride
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