1-butylbiguanide
- CAS NO.：692-13-7
- Empirical Formula: C6H15N5
- Molecular Weight: 157.2168
- MDL number: MFCD00242653
- EINECS: 2117264
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-05 11:31:08
What is 1-butylbiguanide?
The Uses of 1-butylbiguanide
Buformin, clinically used for diabetes mellitus, is known to improve resistance to insulin in patients. It suppresses the expression of glyceraldehyde 3-phosphate dehydrogenase
Definition
ChEBI: Buformin is a member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect. It has a role as a hypoglycemic agent, a geroprotector, a radiosensitizing agent, an antineoplastic agent and an antiviral agent. It is functionally related to a biguanide.
brand name
Adebit;Andebit;Andelit;Andere;Biforon;Bigunal;Biquinal;Bs-5892;Bufonamin;Bulbonin;Diabrin;Dutformin;Gliporal;Insulamin;Krebon;Panformin;Silubin retard;Sindiatil;Tidemol retard;Ziavetine.
World Health Organization (WHO)
Buformin is an analogue of phenformin. See WHO comment for phenformin. (Reference: (WHODI) WHO Drug Information, 2, 4, 1977)
Properties of 1-butylbiguanide
| Melting point: | 174-176 °C |
| Boiling point: | 271.89°C (rough estimate) |
| Density | 1.0291 (rough estimate) |
| refractive index | 1.8070 (estimate) |
| pka | 12.27±0.10(Predicted) |
Safety information for 1-butylbiguanide
Computed Descriptors for 1-butylbiguanide
New Products
Cyclopentane-1,2-dione 8-hydroxy-7-methoxy-2,6-dimethylisoquinolinium iodide Isopropyl amine Hydrochloride 2-Bromo-5-iodopyridine 3-Aminophenylacetic acid Amino-4-methoxyben-zeneacetic acid 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile 1-AMino-cyclobutaneMethanol HCl (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) tri sodium thio phosphate 2-(3-amino propyl amino) ethyl bromide 2,2'-(5-Bromomethyl-1,3-phenylene)-di(2-Methylpropionitrile) L-phenylalanine, N-(pyrazinyl carbonyl) methyl ester 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy Benzylcyanide valeronitrileRelated products of tetrahydrofuran
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