AC-DEVD-AMC
Synonym(s):Ac-DEVD-AMC;Caspase-3 Substrate II, Fluorogenic - CAS 169332-61-0 - Calbiochem
- CAS NO.：169332-61-0
- Empirical Formula: C30H37N5O13
- Molecular Weight: 675.64
- MDL number: MFCD00671411
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is AC-DEVD-AMC?
The Uses of AC-DEVD-AMC
N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin has been used as a substrate for caspase-3 assay in human colon cancer cell line and in bone marrow mesenchymal stem cells.
Biochem/physiol Actions
Fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
Properties of AC-DEVD-AMC
| Boiling point: | 1200.1±65.0 °C(Predicted) |
| Density | 1.423±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: 10 mM |
| form | powder |
| pka | 4.09±0.10(Predicted) |
| color | white |
Safety information for AC-DEVD-AMC
Computed Descriptors for AC-DEVD-AMC
| InChIKey | ALZSTTDFHZHSCA-RNVDEAKXSA-N |
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