AC-DEVD-CHO
Synonym(s):Ac-DEVD-CHO;Caspase-3 Inhibitor I - CAS 169332-60-9 - Calbiochem;CPP32/Apopain Inhibitor, Ac-DEVD-CHO
- CAS NO.：169332-60-9
- Empirical Formula: C20H30N4O11
- Molecular Weight: 502.47
- MDL number: MFCD00671412
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is AC-DEVD-CHO?
The Uses of AC-DEVD-CHO
Reversible inhibitor of interleukin-1beta converting enzyme (ICE); also inhibits caspase-3 cleavage of poly(ADP-ribose) polymerase
The Uses of AC-DEVD-CHO
N-Acetyl-Asp-Glu-Val-Asp-al has been used as a caspase inhibitor in muscle samples, smooth muscle cells and Jurkat T-cells.
Definition
ChEBI: A tetrapeptide consisting of two L-aspartic acid residues, an L-glutamyl residue and an L-valine residue with an acetyl group at the N-terminal and with the C-terminal carboxy group reduced to an aldehyde. It is an inhibitor of caspase-3/7.
General Description
N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) is a tetrapeptide with N-terminal acetylation and C-terminal aldehyde conjugation.
Biochem/physiol Actions
N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) aids in the recovery of stunned myocardium by its caspase inhibition functionality.
Properties of AC-DEVD-CHO
| Boiling point: | 1021.1±65.0 °C(Predicted) |
| Density | 1.374±0.06 g/cm3(Predicted) |
| RTECS | EK7643000 |
| storage temp. | -20°C |
| solubility | H2O: 1 mg/mL |
| pka | 4.19±0.10(Predicted) |
| form | powder |
| color | white |
| Sensitive | Moisture Sensitive |
Safety information for AC-DEVD-CHO
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for AC-DEVD-CHO
New Products
N-Carbethoxy-4-piperidone 1-Aminocyclopentane carbonitrile Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine N-Vinylformamide 4 pentyn 1 ol Phenethyl cinnamate Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
You may like
-
N-Acetyl-Asp-Glu-Val-Asp-al CAS 169332-60-9View Details
169332-60-9 -
Caspase-3 Inhibitor I CAS 169332-60-9View Details
169332-60-9 -
144-83-2 Sulfapyridine 98+View Details
144-83-2 -
29976-53-2 98+View Details
29976-53-2 -
6638-79-5 N,O-Dimethylhydroxylamine hydrochloride 98+View Details
6638-79-5 -
674783-97-2 98+View Details
674783-97-2 -
1-Aminocyclopentane carbonitrile 98+View Details
49830-37-7 -
Tetrabutylammonium perchlorate 1923-70-2 98+View Details
1923-70-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.