A 61603 HYDROBROMIDE
- CAS NO.：107756-30-9
- Empirical Formula: C14H20BrN3O3S
- Molecular Weight: 390.3
- MDL number: MFCD02262217
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-04 19:55:51
What is A 61603 HYDROBROMIDE?
The Uses of A 61603 HYDROBROMIDE
A 61603 is a selective α1A-adrenergic receptor agonist.
What are the applications of Application
A 61603 HYDROBROMIDE is a potent α-adrenoceptor agonist
Biological Activity
Potent α -adrenoceptor agonist that is at least 35-fold more potent at α 1A than at α 1B or α 1D sites. Induces dose response increases in spontaneous Ca 2+ transients in rat ventricular myocytes in vitro (EC 50 = 6.9 nmol/L). Also available as part of the α 1 -Adrenoceptor Tocriset™ .
Storage
Desiccate at +4°C
References
[1]. knepper sm, buckner sa, brune me, et al. a-61603, a potent alpha 1-adrenergic receptor agonist, selective for the alpha 1a receptor subtype. j pharmacol exp ther, 1995, 274(1): 97-103.
[2]. meyer md, altenbach rj, hancock aa, et al. synthesis and in vitro characterization of n-[5-(4,5-dihydro-1h-imidazol-2-yl)-2-hydroxy-5,6,7,8- tetrahydronaphthalen-1-yl]methanesulfonamide and its enantiomers: a novel selective alpha 1a receptor agonist. j med chem, 1996, 39(20): 4116-4119.
[3]. luo dl, gao j, fan ll, et al. receptor subtype involved in alpha 1-adrenergic receptor-mediated ca2+ signaling in cardiomyocytes. acta pharmacol sin, 2007, 28(7): 968-974.
[4]. martínez-salas sg1, campos-peralta jm, pares-hipolito j, et al. alpha1a-adrenoceptors predominate in the control of blood pressure in mouse mesenteric vascular bed. auton autacoid pharmacol, 2007, 27(3): 137-142.
Properties of A 61603 HYDROBROMIDE
| storage temp. | Desiccate at +4°C |
| solubility | Soluble in H2O |
| form | crystalline solid |
| color | White to off-white |
| Water Solubility | Soluble to 50 mM in water |
Safety information for A 61603 HYDROBROMIDE
Computed Descriptors for A 61603 HYDROBROMIDE
New Products
4-Iodo-3,5-dimethylbenzonitrile 2-fluoro-4-iodoaniline 2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 6,6'-methylenebis(9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-2,3-dihydro-1H-carbazol-4(9H)-one) 3-Bromo-2-fluorobenzoic acid Quinuclidine-4-carbonitrile N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (R)-1-Benzyl-3-pyrrolidinecarbonitrile Bupropian related compound F Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 1,4-bis(methylsulfonyl)butane 4-Cyano-N-Methacryloyl-3-Trifluoromethyl Aniline 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzeneRelated products of tetrahydrofuran
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