5,6,7,8-Tetrahydro-1-naphthylamine
Synonym(s):1-Amino-5,6,7,8-tetrahydronaphthalene;5-Aminotetralin
- CAS NO.：2217-41-6
- Empirical Formula: C10H13N
- Molecular Weight: 147.22
- MDL number: MFCD00001736
- EINECS: 218-713-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:55
What is 5,6,7,8-Tetrahydro-1-naphthylamine?
Chemical properties
Clear yellow to brown liquid
The Uses of 5,6,7,8-Tetrahydro-1-naphthylamine
5,6,7,8-Tetrahydro-1-naphthylamine is used as a reagent in the synthesis of GoSlo-SR-5-69, a potent activator of large conductance Ca2+-activated K+ (BK) channels. 5,6,7,8-Tetrahydro-1-naphthylamine is also used as a reagent in the synthesis of benzopyrans and related compounds as inhibitors of the hypoxia inducible factor pathway.
Properties of 5,6,7,8-Tetrahydro-1-naphthylamine
| Melting point: | 38 °C(lit.) |
| Boiling point: | 275-277 °C713 mm Hg(lit.) |
| Density | 1,06 g/cm3 |
| refractive index | n |
| Flash point: | >230 °F |
| solubility | miscible with Alcohol |
| form | Liquid |
| pka | 4.56±0.20(Predicted) |
| color | Clear yellow to brown |
| BRN | 387264 |
| CAS DataBase Reference | 2217-41-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-Naphthalenamine, 5,6,7,8-tetrahydro-(2217-41-6) |
Safety information for 5,6,7,8-Tetrahydro-1-naphthylamine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to..… |
Computed Descriptors for 5,6,7,8-Tetrahydro-1-naphthylamine
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