9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole
- CAS NO.:10371-86-5
- Empirical Formula: C18H16N2O
- Molecular Weight: 276.33
- MDL number: MFCD00049339
- EINECS: 233-812-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is 9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ?
Description
An Ochrosia alkaloid present in O. oppositifolia and O. sandwicensis Gray, it occurs mainly in the bark of these species. It forms light yellow crystals and gives an ultraviolet spectrum in EtOH with absorption maxima at 242, 275, 290 and 335 mil. It may be characterized as the hydrochloride which has m.p. 288- 290°C following a change in crystal form at 255-265°C, or as the picrate, m.p. 273-5°C. The structure has been elucidated from the mass spectrum fragmentation pattern.
Synthesis Reference(s)
The Journal of Organic Chemistry, 72, p. 7106, 2007 DOI: 10.1021/jo070774z
References
Buzas, Osowiecki, Schindler., Cornpt. Rend., 247, 1390 (1958)
Goodwin, Smith, Horning.,!. Arner. Chern. Soc., 81,1903 (1959)
Mass spectrum:
Loder., Austral. J. Chern., 19, 1947 (1966)
Synthesis:
Dalton et aI., Austral. J. Chern., 20, 2715 (1967)
Properties of 9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole
| Melting point: | 286.5°C (rough estimate) |
| Boiling point: | 419.24°C (rough estimate) |
| Density | 1.1318 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| storage temp. | -20°C |
| solubility | DMSO: soluble |
| form | A solid |
| pka | 16.29±0.40(Predicted) |
Safety information for 9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole
Computed Descriptors for 9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole
New Products
9-Mesityl-10-methylacridinium perchlorate Sulfapyridine Fmoc-OSu (R)-(-)-2-Amino-1-propanol Cyclobutanone 5-bromo-4-fluoro-2-nitrobenzaldehyde Phenethyl cinnamate Obidoxime hydrochloride API Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Dipropyl disulfide N-Vinylformamide 4 pentyn 1 ol Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 Carbozantinib intermediate(n-1) N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran



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