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Home Product name list(8S,15S)-DIHETE

(8S,15S)-DIHETE

CAS NO.：80234-65-7
Empirical Formula: C20H32O4
Molecular Weight: 336.47
MDL number: MFCD00063587
SAFETY DATA SHEET (SDS)
Update Date: 2026-07-28 20:33:19

(8S,15S)-DIHETE Structural

What is (8S,15S)-DIHETE?

Description

8(S),15(S)-DiHETE is formed when 15(S)-HETE is subjected to further oxidation by 15-LO. It causes eosinophil chemotaxis with an ED₅₀ value of 1.5 μM but is not chemotactic for neutrophils. 8(S),15(S)-DiHETE antagonizes the hyperalgesic activity of 8(R),15(S)-DiHETE and LTB₄ in the rat hind paw pain model.

The Uses of (8S,15S)-DIHETE

8(S),15(S)-DiHETE (Z, E, Z, E) is a novel dioxygenation product of arachidonic acid.

What are the applications of Application

8(S),15(S)-DiHETE (Z, E, Z, E) is a novel dioxygenation product of arachidonic acid

Definition

ChEBI: 8(S),15(S)-DiHETE is ab 8,15-DiHETE that is derived from (5Z,9E,11Z,13E)-icosatetraenoic acid and has (8S,15S)-stereochemistry. It has a role as a human xenobiotic metabolite and a mouse metabolite. It is functionally related to an arachidonic acid. It is a conjugate acid of an 8(S),15(S)-DiHETE(1-).

Properties of (8S,15S)-DIHETE

storage temp.	−20°C
solubility	DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
form	Colorless liquid.

Safety information for (8S,15S)-DIHETE

Computed Descriptors for (8S,15S)-DIHETE

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(8S,15S)-DIHETE

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8(S),15(S)-DIHETE [1-14C]

8(S),15(S)-DIHETE [1-14C]

5(S),15(S)-DIHETE [1-14C]

5(S),15(S)-DIHETE [1-14C]

5(S), 15(S)-DIHETE

5(S), 15(S)-DIHETE

8(R),15(S)-DIHETE

8(R),15(S)-DIHETE

8(S),15(S)-DIHETE

8(S),15(S)-DIHETE

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