5(S), 15(S)-DIHETE
- CAS NO.：82200-87-1
- Empirical Formula: C20H32O4
- Molecular Weight: 336.47
- MDL number: MFCD00063589
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is 5(S), 15(S)-DIHETE?
Description
5(S),15(S)-
The Uses of 5(S), 15(S)-DIHETE
5(S),15(S)-DiHETE is synthesized by 15-LO from 5(S)-HETE. It potentiates the degranulation of human PMNL in response to PAF, but not fMLP, calcium ionophore A23187, or LTB4. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED50 value of 0.3 μM.
The Uses of 5(S), 15(S)-DIHETE
5(S),15(S)-DiHETE is an enhancer of neutrophil degranulation and potent chemotaxin.
What are the applications of Application
5(S),15(S)-DiHETE is an enhancer of neutrophil degranulation and potent chemotaxin
Definition
ChEBI: 5(S),15(S)-DiHETE is a DiHETE that is (6E,8Z,11Z,13E)-icosatetraenoic acid in which the two hydroxy substituents are placed at the 5S- and 15S-positions. It has a role as a rat metabolite and a human xenobiotic metabolite. It is a conjugate acid of a 5(S),15(S)-DiHETE(1-).
Properties of 5(S), 15(S)-DIHETE
| storage temp. | -20°C |
| solubility | DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml |
| form | Colorless liquid. |
| color | Colorless to light yellow |
Safety information for 5(S), 15(S)-DIHETE
Computed Descriptors for 5(S), 15(S)-DIHETE
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2-(2-Chlorophenyl)glycine Propiolic Acid 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-Pentadecanol 4-(4-Αminophenyl)-3-Morpholinone 3-Morpholino-1-(4-(2-oxopiperidin-1-yl) phenyl)-5,6-dihyropyridin-2-(1H)-one 1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one N-cyanoacetylurethane 1H-IndazoleRelated products of tetrahydrofuran
![8(S),15(S)-DIHETE [1-14C]](https://img.chemicalbook.in/StructureFile/ChemBookStructure8/GIF/CB9304200.gif)
![5(S),15(S)-DIHETE [1-14C]](https://img.chemicalbook.in/StructureFile/ChemBookStructure8/GIF/CB7213551.gif)
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