8-HYDROXYGUANINE
- CAS NO.：5614-64-2
- Empirical Formula: C5H5N5O2
- Molecular Weight: 167.13
- MDL number: MFCD00005564
- EINECS: 227-035-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-09 18:56:23
What is 8-HYDROXYGUANINE?
Chemical properties
White Powder
The Uses of 8-HYDROXYGUANINE
Involved in DNA lesion repair.
The Uses of 8-HYDROXYGUANINE
2-Amino-6,8-dihydroxypurine is an 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase λ.
Definition
ChEBI: An oxopurine that is guanine in which the hydrogen at position 8 is replaced by an oxo group and in which the nitrogens at positions 7 and 9 each bear a hydrogen.
Properties of 8-HYDROXYGUANINE
| Melting point: | >400°C dec. |
| Density | 2.52±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Water: < 0.1 mg/mL (insoluble); Ethanol: < 1 mg/mL (insoluble); DMSO: < 1 mg/mL (insoluble or slightly soluble) |
| form | Solid |
| pka | 8.73±0.20(Predicted) |
| color | Light brown to khaki |
Safety information for 8-HYDROXYGUANINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 8-HYDROXYGUANINE
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