7-Hydroxy-5-methyl-1,3,4-triazaindolizine

Synonym(s):5-Methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-ol;6-Methyl-4-hydroxy-1,3,3a,7-tetraazaindene;7-Hydroxy-5-methyl-1,3,4-triazaindolizine;NSC 32071;NSC 511493

CAS NO.：2503-56-2
Empirical Formula: C6H6N4O
Molecular Weight: 150.14
MDL number: MFCD00005555
EINECS: 219-706-7
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

7-Hydroxy-5-methyl-1,3,4-triazaindolizine Structural

What is 7-Hydroxy-5-methyl-1,3,4-triazaindolizine?

Chemical properties

7-Hydroxy-5-methyl-1,3,4-triazaindolizine is white fine crystalline powder

The Uses of 7-Hydroxy-5-methyl-1,3,4-triazaindolizine

Reactant for the synthesis of: • ;Ruthenium(II)-Hmtpo complexes1• ;Dihydroorotate dehydrogenase inhibitors with antimalarial activity2Reactant for the Vilsmeier reaction of conjugated carbocycles and heterocycles3Investigations of the pharmacological activity caused by binding to HIV TAR RNA4Additive to study the space charge layer in silver bromide microcrystals5

The Uses of 7-Hydroxy-5-methyl-1,3,4-triazaindolizine

Reactant for the synthesis of:

Ruthenium(II)-Hmtpo complexes
Dihydroorotate dehydrogenase inhibitors with antimalarial activity

Reactant for the Vilsmeier reaction of conjugated carbocycles and heterocycles

Investigations of the pharmacological activity caused by binding to HIV TAR RNA

Additive to study the space charge layer in silver bromide microcrystals

Properties of 7-Hydroxy-5-methyl-1,3,4-triazaindolizine

Melting point:	280-283 °C(lit.)
Boiling point:	271.66°C (rough estimate)
Density	1.3471 (rough estimate)
vapor pressure	0-0Pa at 20-25℃
refractive index	1.6700 (estimate)
storage temp.	2-8°C
form	neat
pka	1.14±0.53(Predicted)
color	White to Almost white
Water Solubility	INSOLUBLE IN COLD WATER
BRN	609440
CAS DataBase Reference	2503-56-2(CAS DataBase Reference)
NIST Chemistry Reference	Pyrimidin-7-ol, 5-methyl-s-triazolo-[1,5-a]-(2503-56-2)
EPA Substance Registry System	[1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 5-methyl- (2503-56-2)

Safety information for 7-Hydroxy-5-methyl-1,3,4-triazaindolizine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.