7-Fluoro-6-nitro-4-hydroxyquinazoline
- CAS NO.：162012-69-3
- Empirical Formula: C8H4FN3O3
- Molecular Weight: 209.13
- MDL number: MFCD08458874
- EINECS: 1308068-626-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-24 18:13:46
What is 7-Fluoro-6-nitro-4-hydroxyquinazoline?
The Uses of 7-Fluoro-6-nitro-4-hydroxyquinazoline
7-Fluoro-6-nitroquinazolin-4(3H)-one, is an intermediate in the preparation of kinase inhibitors, such as ATP Site inhibitors of the Tyrosine Kinase activity of the epidermal growth factor receptor.
Properties of 7-Fluoro-6-nitro-4-hydroxyquinazoline
| Melting point: | 282-285 °C(Solv: acetic acid (64-19-7)) |
| Boiling point: | 407.6±55.0 °C(Predicted) |
| Density | 1.75±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | -2.69±0.20(Predicted) |
| form | powder to crystal |
| color | Light yellow to Yellow to Orange |
| CAS DataBase Reference | 162012-69-3(CAS DataBase Reference) |
Safety information for 7-Fluoro-6-nitro-4-hydroxyquinazoline
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. |
Computed Descriptors for 7-Fluoro-6-nitro-4-hydroxyquinazoline
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