6,9-Dichloro-2-methoxyacridine
- CAS NO.：86-38-4
- Empirical Formula: C14H9Cl2NO
- Molecular Weight: 278.13
- MDL number: MFCD00005028
- EINECS: 201-666-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-23 17:25:30
What is 6,9-Dichloro-2-methoxyacridine?
The Uses of 6,9-Dichloro-2-methoxyacridine
6,9-Dichloro-2-methoxyacridine is used to prepare 6-chloro-2-methoxy-acridin-9-ylamine by reacting with phenol and ammonium carbonate. It is used in the preparation of 9-amino-6-chloro-2-methoxyacridine, N'-(6-Chloro-2-methoxy-acridin-9-yl)-heptylamine and N,N'-bis-(6-chloro-2-methoxy-acridin-9-yl)-hexane-1,6-diamine. Further, it is involved in the preparation of 4-aminoquinoline and 9-aminoacridine derivatives by reaction with quinolizidinylalkylamines.
General Description
6,9-Dichloro-2-methoxyacridine on reaction with quinolizidinylalkylamines yields 4-aminoquinoline and 9-aminoacridine derivatives.
Purification Methods
Crystallise it from *benzene or 1,2-dichloroethane (m 162-163o). [Hall & Turner J Chem Soc 697 1945, Beilstein 21 III/IV 1553.]
Properties of 6,9-Dichloro-2-methoxyacridine
| Melting point: | 163-165 °C (lit.) |
| Boiling point: | 444.3±25.0 °C(Predicted) |
| Density | 1.52 g/cm3 |
| storage temp. | 2-8°C |
| pka | 2.98±0.10(Predicted) |
| Water Solubility | Insoluble in water. |
| BRN | 226309 |
| CAS DataBase Reference | 86-38-4(CAS DataBase Reference) |
Safety information for 6,9-Dichloro-2-methoxyacridine
| Signal word | Danger |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H334:Sensitisation, respiratory H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 6,9-Dichloro-2-methoxyacridine
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