6,7,8-TRIMETHOXYCOUMARIN
- CAS NO.：6035-49-0
- Empirical Formula: C12H12O5
- Molecular Weight: 236.22
- MDL number: MFCD00145039
- EINECS: 200-485-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is 6,7,8-TRIMETHOXYCOUMARIN?
Chemical properties
White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Fraxinuschinensis Roxb.
The Uses of 6,7,8-TRIMETHOXYCOUMARIN
Dimethylfraxetin has a bactericidal, anti-inflammatory, anti-radiation damage, and immune-enhancing effects.
Definition
ChEBI: 6,7,8-trimethoxy-1-benzopyran-2-one is a member of coumarins.
Biological Activity
Dimethylfraxetin is a Carbonic anhydrase inhibitor with a Ki of 0.0097 μM.
in vitro
At CA I there is one stand out compound being Dimethylfraxetin (compound 17), a nanomolar CA I inhibitor. This trimethoxy coumarin is the most potent of any of the NP coumarins across the six CA isozymes of the present study .
Properties of 6,7,8-TRIMETHOXYCOUMARIN
| Melting point: | 104-105°C |
| Boiling point: | 338.68°C (rough estimate) |
| Density | 1.249 |
| refractive index | 1.5140 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO : 125 mg/mL (529.17 mM; Need ultrasonic and warming) |
| form | Cryst. |
| color | White to yellow |
Safety information for 6,7,8-TRIMETHOXYCOUMARIN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for 6,7,8-TRIMETHOXYCOUMARIN
New Products
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