6-PHENYL-3(2H)-PYRIDAZINONE
- CAS NO.：2166-31-6
- Empirical Formula: C10H8N2O
- Molecular Weight: 172.18
- MDL number: MFCD00114953
- EINECS: 218-505-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 06:33:06
What is 6-PHENYL-3(2H)-PYRIDAZINONE?
The Uses of 6-PHENYL-3(2H)-PYRIDAZINONE
6-Phenylpyridazin-3(2H)-one is a reagent in the preparation of cyclase activator Runcaciguat, a compound used in the treatment of kidney disease and non-proliferative diabetic retinopathy.
General Description
6-Phenyl-3(2H)-pyridazinone is a pyridazinone derivative that can be prepared from 4,5- dihydro-6-phenyl-3(2H)-pyridazinone. It is reported to be a weak positive inotropic agent. 6-Phenyl-3(2H)-pyridazinone forms the core of compounds that show a potential antiplatelet activity.
Properties of 6-PHENYL-3(2H)-PYRIDAZINONE
| Melting point: | 201-204 °C(lit.) |
| Density | 1.20±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 11.05±0.40(Predicted) |
| color | White to Light yellow |
| λmax | 249nm(HCl aq.)(lit.) |
Safety information for 6-PHENYL-3(2H)-PYRIDAZINONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 6-PHENYL-3(2H)-PYRIDAZINONE
| InChIKey | IJUIPRDMWWBTTQ-UHFFFAOYSA-N |
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![6-PHENYL-5-[(1,1,1-TRIPHENYL-LAMBDA5-PHOSPHANYLIDENE)AMINO]-2,3-DIHYDROPYRIDAZIN-3-ONE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB1461912.gif)
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