6 beta-hydroxycortisol
- CAS NO.：53-35-0
- Empirical Formula: C21H30O6
- Molecular Weight: 378.46
- MDL number: MFCD00200405
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:56
What is 6 beta-hydroxycortisol?
Chemical properties
Off-White to Pale Yellow Solid
The Uses of 6 beta-hydroxycortisol
A metabolite of Cortisol
Definition
ChEBI: 6beta-hydroxycortisol is a C21-steroid that is cortisol bearing an additional hydroxy substituent at the 6beta-position. In humans, it is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo. It has a role as a mammalian metabolite, a human metabolite and a probe. It is a C21-steroid, a 6beta-hydroxy steroid, a 3-oxo-Delta(4) steroid, a 21-hydroxy steroid, a 20-oxo steroid, a 17alpha-hydroxy steroid, an 11beta-hydroxy steroid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It is functionally related to a cortisol.
Properties of 6 beta-hydroxycortisol
| Melting point: | 182-190?C |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Pale Yellow |
Safety information for 6 beta-hydroxycortisol
Computed Descriptors for 6 beta-hydroxycortisol
6 beta-hydroxycortisol manufacturer
Clickchem Research LLP
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