11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
Synonym(s):11β,17α-Dihydroxy-4-pregnene-3,20-dione;11β,17α-Dihydroxyprogesterone;21-Desoxycortisol;4-Pregnene-11β,17α-diol-3,20-dione
- CAS NO.：641-77-0
- Empirical Formula: C21H30O4
- Molecular Weight: 346.46
- MDL number: MFCD00056476
- EINECS: 211-375-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:40
What is 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE?
Chemical properties
Pale Yellow Solid
The Uses of 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
A metabolite of Fluticasone propionate (F599500).
The Uses of 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
21-Deoxy Cortisol (Hydrocortisone EP Impurity L) is a metabolite of Fluticasone propionate (F599500).
Definition
ChEBI: 21-deoxycortisol is a deoxycortisol that is 17xi-pregn-4-ene-3,20-dione substituted by a beta-hydroxy group at position 11 and an alpha-hydroxy group at position 17. It is a marker of virilizing adrenal hyperplasia caused by 21-hydroxylase deficiency. It has a role as a human blood serum metabolite and a mouse metabolite. It is an 11beta-hydroxy steroid, a 17alpha-hydroxy-C21-steroid, a tertiary alpha-hydroxy ketone and a deoxycortisol.
Properties of 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
| Melting point: | 225-228 °C |
| Boiling point: | 523.9±50.0 °C(Predicted) |
| Density | 1.21±0.1 g/cm3(Predicted) |
| Flash point: | 9℃ |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 12.86±0.70(Predicted) |
| color | White to Pale Yellow |
Safety information for 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H370:Specific target organ toxicity, single exposure |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
New Products
DL-beta-(3-Bromophenyl)alanine 1-Aminocyclopentane carbonitrile (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate Amlodipine EP Impurity-C Budesonide Impurity-K/Budesonide 21-Acetate (Epimers) Gabapentine Impurity 72 Bicalutamide Impurity-B Betahistine EP Impurity C Carbamazepine EP Impurity G 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene 5-Methyl-1,3-benzenediacetonitrile (R)-BoroLeu-(+)-Pinanediol-CF3COOH 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 3-Hydroxypropionitrile 4-Bromo Benzylcyanide valeronitrile 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanide 2-Chloro BenzylcyanideRelated products of tetrahydrofuran
![HYDROCORTISONE-[1,2,6,7-3H(N)]](https://img.chemicalbook.in/CAS/GIF/70094-60-9.gif)
![CORTISOL [1,2-3H(N)]-](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB8469593.gif)
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