6-Amino-2,2-dimethyl-2H-pyrido[3,2-B][1,4]oxazin-3(4H)-one

CAS NO.：1002726-62-6
Empirical Formula: C9H11N3O2
Molecular Weight: 193.2
MDL number: MFCD10000812
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-27 17:24:12

What is 6-Amino-2,2-dimethyl-2H-pyrido[3,2-B][1,4]oxazin-3(4H)-one?

The Uses of 6-Amino-2,2-dimethyl-2H-pyrido[3,2-B][1,4]oxazin-3(4H)-one

6-Amino-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one is a useful intermediate for the preparation of protein kinase inhibitors.

What are the applications of Application

6-amino-2,2-dimethyl-2h-pyrido[3,2-b][1,4]oxazin-3(4h)-one is the key intermediate of Fostamatinib, which is a medication approved by the U.S. Food and Drug Administration since 2018 for the treatment of chronic immune thrombocytopenia (ITP).

Properties of 6-Amino-2,2-dimethyl-2H-pyrido[3,2-B][1,4]oxazin-3(4H)-one

Boiling point:	420.3±45.0 °C(Predicted)
Density	1.256
Flash point:	208
storage temp.	2-8°C(protect from light)
form	solid
pka	10.79±0.40(Predicted)
form	solid
InChI	InChI=1S/C9H11N3O2/c1-9(2)8(13)12-7-5(14-9)3-4-6(10)11-7/h3-4H,1-2H3,(H3,10,11,12,13)

Safety information for 6-Amino-2,2-dimethyl-2H-pyrido[3,2-B][1,4]oxazin-3(4H)-one

Computed Descriptors for 6-Amino-2,2-dimethyl-2H-pyrido[3,2-B][1,4]oxazin-3(4H)-one

InChIKey	HSYOWUOUDXDSMC-UHFFFAOYSA-N
SMILES	O1C(C)(C)C(=O)NC2=NC(N)=CC=C12

6-Amino-2,2-dimethyl-2H-pyrido[3,2-B][1,4]oxazin-3(4H)-one manufacturer

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product: 6-Amino-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one 1002726-62-6 97-99 %

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