5,6-Dihydro-2H-pyran-2-one
- CAS NO.：3393-45-1
- Empirical Formula: C5H6O2
- Molecular Weight: 98.1
- MDL number: MFCD00010439
- EINECS: 628-075-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:49:01
What is 5,6-Dihydro-2H-pyran-2-one?
The Uses of 5,6-Dihydro-2H-pyran-2-one
5,6-Dihydro-2H-pyran-2-one has been used in the preparation of:
- (1aR,5aR,5bS,6S,7S)-6,7-di-tert-butoxy-5-oxo-pyrrolidino[1,2-b]isoxazolidino[4,5-c]tetrahydropyran
- 4-(phenyl)tetrahydro-2H-pyran-2-one
Synthesis Reference(s)
The Journal of Organic Chemistry, 49, p. 1647, 1984 DOI: 10.1021/jo00183a030
Tetrahedron Letters, 25, p. 4783, 1984 DOI: 10.1016/S0040-4039(01)81518-5
General Description
Enantioselective conjugate addition of Grignard reagents to 5,6-dihydro-2H-pyran-2-one catalyzed by a chiral phosphine-copper iodide catalyst has been reported.
Properties of 5,6-Dihydro-2H-pyran-2-one
| Boiling point: | 103 °C/10 mmHg (lit.) |
| Density | 1.139 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 115 °F |
| storage temp. | 2-8°C |
| form | clear liquid |
| color | Colorless to Light orange to Yellow |
| Sensitive | Moisture Sensitive |
| BRN | 1610 |
| CAS DataBase Reference | 3393-45-1 |
Safety information for 5,6-Dihydro-2H-pyran-2-one
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02 |
| GHS Hazard Statements |
H226:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..… |
Computed Descriptors for 5,6-Dihydro-2H-pyran-2-one
| InChIKey | QBDAFARLDLCWAT-UHFFFAOYSA-N |
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