5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
- CAS NO.：1434-54-4
- Empirical Formula: C22H31NO2
- Molecular Weight: 341.49
- MDL number: MFCD00079212
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-08-04 11:17:55
What is 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE?
The Uses of 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
Pregnenolone Carbonitrile is a glucocorticoid receptor antagonist that induces the expression of the CYP3A family of steroid hydroxylases and modulates sterol and bile acid biosynthesis in vivo. Pregnenolone Carbonitrile is an an activator of rat pregnane X receptor (PXR).
What are the applications of Application
5-Pregnen-3β-ol-20-one-16α-carbonitrile is an activator of Cyp2c55
Definition
ChEBI: Pregnenolone 16alpha-carbonitrile is an aliphatic nitrile. It is functionally related to a pregnenolone.
Biochem/physiol Actions
Pregnenolone-16a-carbonitrile (PCN) is a glucocorticoid receptor antagonist and a PXR (pregnane X receptor) activator.
Properties of 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
| Melting point: | 225-228 °C(Solv: methanol (67-56-1); benzene (71-43-2)) |
| Boiling point: | 508.5±50.0 °C(Predicted) |
| Density | 1.13±0.1 g/cm3(Predicted) |
| Flash point: | 93 °C |
| storage temp. | 2-8°C |
| solubility | Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml |
| form | White to off-white solid. |
| pka | 14.95±0.70(Predicted) |
| color | White to off-white |
| EPA Substance Registry System | Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3.beta.,16.alpha.)- (1434-54-4) |
Safety information for 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
Computed Descriptors for 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE manufacturer
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