5-Aminolevulinic acid methyl ester hydrochloride
Synonym(s):5-Amino-4-oxopentanoic acid methyl ester;5-Aminolevulinic acid methyl ester
- CAS NO.：79416-27-6
- Empirical Formula: C6H12ClNO3
- Molecular Weight: 181.62
- MDL number: MFCD00012868
- EINECS: 279-151-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-20 19:14:41
What is 5-Aminolevulinic acid methyl ester hydrochloride?
Chemical properties
5-Aminolevulinic acid methyl ester hydrochloride is white powder
The Uses of 5-Aminolevulinic acid methyl ester hydrochloride
5-Aminolevulinic acid methyl ester hydrochloride is used in photodynamic therapy.
Definition
ChEBI: The hydrochloride salt of methyl 5-aminolevulinate. A prodrug, it is metabolised to protoporphyrin IX, a photosensitizer, and is used in the photodynamic treatment of non-melanoma skin cancer (including basal cell carcinoma). Topical application results in an accumulation of protoporphyrin IX in the skin lesions to which the cream has been applied. Subsequent illumination with red light results in the generation of toxic singlet oxygen that destroys cell membranes and thereby kills the tumour cells.
brand name
Metvixia (PhotoCure, Norway).
Biochem/physiol Actions
Methyl δ-aminolevulinate (methyl-ALA, MAL) and 5-Aminolevulinic acid (5-ALA) are commonly used in photosentizer reagents for photodynamic therapy to treat conditions such as Acne vulgaris and hypertrophic scarring.
Properties of 5-Aminolevulinic acid methyl ester hydrochloride
| Melting point: | 119-121° |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | very faint turbidity |
| Sensitive | Light Sensitive/Hygroscopic |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 79416-27-6(CAS DataBase Reference) |
Safety information for 5-Aminolevulinic acid methyl ester hydrochloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-Aminolevulinic acid methyl ester hydrochloride
| InChIKey | UJYSYPVQHFNBML-UHFFFAOYSA-N |
New Products
Paroxetine Impurity G/Paroxetine Related Compound E 1-Aminocyclopentane carbonitrile (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate (R)-1-Benzyl-3-pyrrolidinecarbonitrile Betahistine EP Impurity C Cyclobenzaprine N-oxide/Citalopram Related Compound E Chlorthalidone Impurity I Carbamazepine EP Impurity G Sumatriptan Succinate USP Related Compound C 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene 5-Methyl-1,3-benzenediacetonitrile (R)-BoroLeu-(+)-Pinanediol-CF3COOH 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 4-Bromo Benzylcyanide 3-Hydroxypropionitrile valeronitrile 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanide 2-Chloro BenzylcyanideRelated products of tetrahydrofuran
You may like
-
Methyl 5-Aminolevulinate Hydrochloride CAS 79416-27-6View Details
79416-27-6 -
Methyl δ-aminolevulinate hydrochloride CAS 79416-27-6View Details
79416-27-6 -
2847776-12-7 Sumatriptan Succinate USP Related Compound C NLT 95%View Details
2847776-12-7 -
1012886-75-7(HCl Salt)/69675-10-1(Freebase) Paroxetine Impurity G/Paroxetine Related Compound E NLT 95%View Details
1012886-75-7(HCl Salt)/69675-10-1(Freebase) -
3,4 Diethoxy Benzylcyanide 99%View Details
27472-21-5 -
Bromoacetaldehyde Dimethyl Acetal (stabilized with K2CO3)View Details
7252-83-7 -
157528-56-8 (R)-1-Benzyl-3-pyrrolidinecarbonitrile 98+View Details
157528-56-8 -
157528-56-8 (R)-1-Benzyl-3-pyrrolidinecarbonitrile 98+View Details
157528-56-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.