4-tert-Butylcyclohexanecarboxylic acid

CAS NO.：5451-55-8
Empirical Formula: C11H20O2
Molecular Weight: 184.28
MDL number: MFCD00042622
SAFETY DATA SHEET (SDS)
Update Date: 2026-09-12 18:48:18

What is 4-tert-Butylcyclohexanecarboxylic acid?

Chemical properties

WHITE FINE CRYSTALS OR CRYSTALLINE POWDER

The Uses of 4-tert-Butylcyclohexanecarboxylic acid

4-tert-Butylcyclohexanecarboxylic Acid has been used as a reactant in the synthesis of cycloalkylamide derivatives as inhibitors of soluble epoxide hydrolase.

The Uses of 4-tert-Butylcyclohexanecarboxylic acid

4-tert-Butylcyclohexanecarboxylic acid may be used in the preparation of N-((S)-3-(4-(7-chloroquinolin-4-yl)piperazin-1-yl)-1-henylpropyl)-4-tert-butylcyclohexanecarboxamide.

What are the applications of Application

4-tert-Butylcyclohexanecarboxylic acid is Used to prepare N-((S)-3-(4-(7-chloroquinolin-4-yl)piperazin-1-yl)-1-henylpropyl)-4-tert-butylcyclohexanecarboxamide

Definition

ChEBI: Trans-4-tert-butylcyclohexanecarboxylic acid is a monocarboxylic acid that is cyclohexanecarboxylic acid substituted by a tert-butyl group at position 4 (the trans-stereoisomer). It has a role as a metabolite. It derives from a hydride of a cyclohexane.

General Description

delta pKa between the two stereoisomers of 4-tert-butylcyclohexanecarboxylic acid has been studied using 1H and 13C NMR. Preparation of cis- and trans-4-tert- butylcyclohexanecarboxylic acid has been reported.

Properties of 4-tert-Butylcyclohexanecarboxylic acid

Melting point:	148 °C (lit.)
Boiling point:	282.9±8.0 °C(Predicted)
Density	0.996±0.06 g/cm3(Predicted)
storage temp.	Store below +30°C.
solubility	soluble in Methanol
form	powder to crystal
pka	4.92±0.10(Predicted)
color	White to Almost white
BRN	2043187
CAS DataBase Reference	5451-55-8(CAS DataBase Reference)

Safety information for 4-tert-Butylcyclohexanecarboxylic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.