4-[(S)-[(2S,5R)-2,5-Dimethyl-4-(2-propenyl)-1-piperazinyl]phenylmethyl]-N,N-diethylbenzamide

CAS NO.：178803-51-5
Empirical Formula: C27H37N3O
Molecular Weight: 419.6
MDL number: MFCD04307698
SAFETY DATA SHEET (SDS)
Update Date: 2026-09-12 18:47:37

What is 4-[(S)-[(2S,5R)-2,5-Dimethyl-4-(2-propenyl)-1-piperazinyl]phenylmethyl]-N,N-diethylbenzamide?

The Uses of 4-[(S)-[(2S,5R)-2,5-Dimethyl-4-(2-propenyl)-1-piperazinyl]phenylmethyl]-N,N-diethylbenzamide

Opioid agonists exert a broad range of effects on the immune system ranging from inflammatory response modulation to opioid and chemokine receptor expression. SNC 162 is a selective δ-opioid receptor agonist.

What are the applications of Application

SNC 162 is a selective non-peptidic DOR (δ-opioid receptor) agonist

Definition

ChEBI: 4-[(S)-[(2S,5R)-2,5-dimethyl-4-prop-2-enyl-1-piperazinyl]-phenylmethyl]-N,N-diethylbenzamide is a diarylmethane.

Biological Activity

Potent and selective non-peptide δ -opioid receptor agonist (K i = 0.63 nM). Displays > 8000-fold selectivity over μ -opioid receptors and is centrally active following systemic administration in vivo .

Storage

Store at RT

Properties of 4-[(S)-[(2S,5R)-2,5-Dimethyl-4-(2-propenyl)-1-piperazinyl]phenylmethyl]-N,N-diethylbenzamide

Boiling point:	536.4±50.0 °C(Predicted)
Density	1.027
storage temp.	Store at RT
solubility	Soluble to 100 mM in 1eq. HCl
form	Powder
pka	7.28±0.10(Predicted)
color	White to off-white

Safety information for 4-[(S)-[(2S,5R)-2,5-Dimethyl-4-(2-propenyl)-1-piperazinyl]phenylmethyl]-N,N-diethylbenzamide

Computed Descriptors for 4-[(S)-[(2S,5R)-2,5-Dimethyl-4-(2-propenyl)-1-piperazinyl]phenylmethyl]-N,N-diethylbenzamide

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