4-MALEIMIDO-TEMPO
Synonym(s):4-Maleimido-2,2,6,6-tetramethyl-1-piperidinyloxy, free radical
- CAS NO.：15178-63-9
- Empirical Formula: C13H19N2O3*
- Molecular Weight: 251.3
- MDL number: MFCD00010110
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:23:39
What is 4-MALEIMIDO-TEMPO?
Chemical properties
Red-Orange Solid
The Uses of 4-MALEIMIDO-TEMPO
4-Maleimido-TEMPO (4-Maleimido-2,2,6,6,-tetramethylpiperidinooxyl) was employed as spin label to investigate the influence of bile salts on the intact rat mitochondrial membranes by electron paramagnetic resonance spectroscopy (EPR). It may be employed as spin label for the labeling of erythrocyte membranes to investigate the interaction of quercetin with erythrocyte proteins by EPR spectra.
The Uses of 4-MALEIMIDO-TEMPO
A thiol specific spin label.
What are the applications of Application
N-(1-Oxyl-2,2,6,6-tetramethyl-4-piperidinyl)maleimide is A thiol specific spin label
Definition
ChEBI: 4-maleimido-TEMPO is a member of the class of piperidines that is TEMPO carrying a maleimido group at position 4. It has a role as a radical scavenger and a spin label. It is a member of aminoxyls, a member of piperidines, a member of maleimides and a dicarboximide. It is functionally related to a TEMPO.
General Description
4-Maleimido-TEMPO, a water-soluble nitroxide radical, is commonly employed as spin probe. It has been reported to inhibit the survival of CHO cells at 1mM concentrations. It is widely employed maleimide spin label for EPR studies.
Biochem/physiol Actions
Spin label used to study fluidity of brain synaptosomal membranes, internal microviscosity of erythrocytes, and human high density lipoproteins.
Properties of 4-MALEIMIDO-TEMPO
| Melting point: | 91-94 °C |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Orange to Dark Orange |
Safety information for 4-MALEIMIDO-TEMPO
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-MALEIMIDO-TEMPO
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