4-Hydroxyphthalic acid
- CAS NO.:610-35-5
- Empirical Formula: C8H6O5
- Molecular Weight: 182.13
- MDL number: MFCD00013984
- EINECS: 210-221-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-06 15:52:27
What is 4-Hydroxyphthalic acid?
Chemical properties
off-white to white powder
The Uses of 4-Hydroxyphthalic acid
4-Hydroxyphthalic acid is used as a precursor to prepare 3,5-dichloro-4-hydroxyphthalic acid using the reagent aqueous acetic acid and chlorine. Further, it is also used as a starting material in the manufacture of N-(4-carboxyphenyl)-4-acetoxyphthalimide.
Definition
ChEBI: 4-hydroxyphthalic acid is a hydroxybenzoic acid that is phthalic acid in which the hydrogen at position 4 is substituted by a hydroxy group. It is a member of phenols and a hydroxybenzoic acid. It derives from a phthalic acid.
Properties of 4-Hydroxyphthalic acid
| Melting point: | 191-194 °C |
| Boiling point: | 235.5°C (rough estimate) |
| Density | 1.3293 (rough estimate) |
| refractive index | 1.4330 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Powder |
| pka | 3.13±0.10(Predicted) |
| color | White to off-white |
| Water Solubility | Slightly miscible with water. |
| CAS DataBase Reference | 610-35-5(CAS DataBase Reference) |
| EPA Substance Registry System | 1,2-Benzenedicarboxylic acid, 4-hydroxy- (610-35-5) |
Safety information for 4-Hydroxyphthalic acid
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P321:Specific treatment (see … on this label). P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 4-Hydroxyphthalic acid
New Products
DL-beta-(3-Bromophenyl)alanine 1-Aminocyclopentane carbonitrile (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine(RM for Indian lab) Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate Amlodipine EP Impurity-C Budesonide Impurity-K/Budesonide 21-Acetate (Epimers) Gabapentine Impurity 72 Bicalutamide Impurity-B Betahistine EP Impurity C Carbamazepine EP Impurity G 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene 5-Methyl-1,3-benzenediacetonitrile (R)-BoroLeu-(+)-Pinanediol-CF3COOH 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 3-Hydroxypropionitrile 4-Bromo Benzylcyanide valeronitrile 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanide 2-Chloro BenzylcyanideRelated products of tetrahydrofuran








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