4-Hydroxyphthalic acid
- CAS NO.:610-35-5
- Empirical Formula: C8H6O5
- Molecular Weight: 182.13
- MDL number: MFCD00013984
- EINECS: 210-221-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-06 15:52:27
What is 4-Hydroxyphthalic acid?
Chemical properties
off-white to white powder
The Uses of 4-Hydroxyphthalic acid
4-Hydroxyphthalic acid is used as a precursor to prepare 3,5-dichloro-4-hydroxyphthalic acid using the reagent aqueous acetic acid and chlorine. Further, it is also used as a starting material in the manufacture of N-(4-carboxyphenyl)-4-acetoxyphthalimide.
Definition
ChEBI: 4-hydroxyphthalic acid is a hydroxybenzoic acid that is phthalic acid in which the hydrogen at position 4 is substituted by a hydroxy group. It is a member of phenols and a hydroxybenzoic acid. It derives from a phthalic acid.
Properties of 4-Hydroxyphthalic acid
| Melting point: | 191-194 °C |
| Boiling point: | 235.5°C (rough estimate) |
| Density | 1.3293 (rough estimate) |
| refractive index | 1.4330 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Powder |
| pka | 3.13±0.10(Predicted) |
| color | White to off-white |
| Water Solubility | Slightly miscible with water. |
| CAS DataBase Reference | 610-35-5(CAS DataBase Reference) |
| EPA Substance Registry System | 1,2-Benzenedicarboxylic acid, 4-hydroxy- (610-35-5) |
Safety information for 4-Hydroxyphthalic acid
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P321:Specific treatment (see … on this label). P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 4-Hydroxyphthalic acid
New Products
Tridecanoic acid 3-Bromophenylacetic acid 3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Hendecanoic acid 2-Amino-5-cyanopyridine 2-Bromo-5-cyanopyridine 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 5-Bromo-4-chloro-3-indolyl-β-D-galactopyranoside Tetracaine Hydrochloride Ep Grade 2,2,2-Trichloroethyl chloroformate 3′-Hydroxyacetophenone 5-fluoro-1,3-benzodioxole 2-Bromo-6-fluoroaniline Methyl-5-chloro-2-hdyroxy-3-nitro benzoate 5-(2,4-Difluorophenyl) isoxazole-3-carboxylicacid Methyl-5-(3-nitrophenyl)isoxazole-3-carboxylate 2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone Methl-4-(chlorophenyl)-2,4-dioxo butanoate 2-Morpholino nicotinicacid 5-amino-1-(2-chlorophenyl)-1H-pyrazole-4-carbonitrile ethyl 1-(6-chloropyridin-2-yl)-5-hydroxy-1H-pyrazole-4-carboxylate N-[-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-(methyl-d3)-1-naphthalenemethanamine, monohydrochloride 2H-indol-2-one, 5-amino-1,3-dihydro-1-(1-methylethyl)- Nifedipine D6Related products of tetrahydrofuran








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