4-CARBOXY-2,2,6,6-TETRAMETHYLPIPERIDINE 1-OXYL

Synonym(s):4-Carboxy-2,2,6,6-tetramethylpiperidine 1-oxyl;4-Carboxy-2,2,6,6-tetramethylpiperidinyloxy, free radical;4-Carboxy-TEMPO

CAS NO.：37149-18-1
Empirical Formula: C10H18NO3*
Molecular Weight: 200.25
MDL number: MFCD00134569
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 03:54:05

4-CARBOXY-2,2,6,6-TETRAMETHYLPIPERIDINE 1-OXYL Structural

What is 4-CARBOXY-2,2,6,6-TETRAMETHYLPIPERIDINE 1-OXYL?

The Uses of 4-CARBOXY-2,2,6,6-TETRAMETHYLPIPERIDINE 1-OXYL

4-Carboxy-TEMPO may be employed as catalyst for the oxidation of regenerated cellulose (viscose rayon) to cellouronic acid. 4-Carboxy-TEMPO is a 4-substituted 2,2,6,6-tetramethylpiperidyl-1-oxy (TEMPO) derivative. 4-carboxy-TEMPO immobilized with 3-aminopropylsilane on the mesoporous silica surface comprises heterogeneous catalytic system employed for various oxidation reactions.

What are the applications of Application

4-Carboxy-TEMPO, free radical is a spin label compound

Definition

ChEBI: 4-carboxy-TEMPO is a member of the class of aminoxyls that is TEMPO carrying a carboxy group at position 4. It has a role as a radical scavenger, a MRI contrast agent and a spin label. It is a member of aminoxyls and a piperidinemonocarboxylic acid. It is functionally related to a TEMPO.

General Description

4-Carboxy-TEMPO is a 4-substituted 2,2,6,6-tetramethylpiperidyl-1-oxy (TEMPO) derivative. 4-carboxy-TEMPO immobilized with 3-aminopropylsilane on the mesoporous silica surface comprises heterogeneous catalytic system employed for various oxidation reactions.

Properties of 4-CARBOXY-2,2,6,6-TETRAMETHYLPIPERIDINE 1-OXYL

Melting point:	185-189 °C(lit.)
storage temp.	2-8°C
solubility	DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form	powder to crystal
color	Light yellow to Brown
BRN	3949026

Safety information for 4-CARBOXY-2,2,6,6-TETRAMETHYLPIPERIDINE 1-OXYL

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.