4-Biphenylcarbonyl chloride
Synonym(s):4-Phenylbenzoyl chloride
- CAS NO.：14002-51-8
- Empirical Formula: C13H9ClO
- Molecular Weight: 216.66
- MDL number: MFCD00000692
- EINECS: 237-804-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-12 09:11:21
What is 4-Biphenylcarbonyl chloride?
Chemical properties
4-Biphenylcarbonyl chloride is white to yellow fine crystalline powder
The Uses of 4-Biphenylcarbonyl chloride
Biphenyl-4-carbonyl chloride was used in the preparation of a novel thiourea compound, N-(6-methyl pyridin-2-yl-carbamothioyl)biphenyl-4-carboxamide. It was also used in the preparation of 5-CF3-oxazole analog, 2-{4-[2-(2-biphenyl-4-yl-5-trifluoromethyl-oxazol-4-yl)-ethoxy]-phenoxy}-2-methyl-propionic acid.
What are the applications of Application
Biphenyl-4-carbonyl chloride is used in the preparation of a novel thiourea compound, N-(6-methyl pyridin-2-yl-carbamothioyl)biphenyl-4-carboxamide
Purification Methods
Dissolve the carbonyl chloride in a large volume of pet ether (10 x, b 50-70o), filter it through a short column of neutral alumina, evaporate to dryness in vacuo and recrystallise it from pet ether (b 60-80o). [Beilstein 9 IV 2480.] LACHRYMATORY.
Properties of 4-Biphenylcarbonyl chloride
| Melting point: | 110-112 °C (lit.) |
| Boiling point: | 160 °C / 2mmHg |
| Density | 1.1459 (rough estimate) |
| refractive index | 1.5260 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | Fine Crystalline Powder |
| color | White to yellow |
| Water Solubility | HYDROLYSIS |
| Sensitive | Moisture Sensitive/Lachrymatory |
| BRN | 472842 |
| CAS DataBase Reference | 14002-51-8(CAS DataBase Reference) |
| EPA Substance Registry System | [1,1'-Biphenyl]-4-carbonyl chloride (14002-51-8) |
Safety information for 4-Biphenylcarbonyl chloride
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Biphenylcarbonyl chloride
| InChIKey | JPVUWCPKMYXOKW-UHFFFAOYSA-N |
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amineRelated products of tetrahydrofuran
You may like
-
4-Phenylbenzoyl Chloride CAS 14002-51-8View Details
14002-51-8 -
Biphenyl-4-carbonyl chloride CAS 14002-51-8View Details
14002-51-8 -
2-Bromo-4-nitropyridine-N-oxide 52092-43-0 98%View Details
52092-43-0 -
18979-61-8 98%View Details
18979-61-8 -
4, 4'-Ditolylamine (or) 4,4-Dimethyl Diphenylamine 620-93-9 98%View Details
620-93-9 -
2-Bromo-5-Chloropyridine 98%View Details
40473-01-6 -
2-(2,4-Diaminophenoxy)ethanol Dihydrochloride 98%View Details
66422-95-5 -
Eperisone Hydrochloride APIView Details
56839-43-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.