4-[(4-Methylpiperazin-1-yl)methyl]aniline
- CAS NO.:70261-82-4
- Empirical Formula: C12H19N3
- Molecular Weight: 205.3
- MDL number: MFCD03725418
- EINECS: 200-158-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:31:50
What is 4-[(4-Methylpiperazin-1-yl)methyl]aniline?
The Uses of 4-[(4-Methylpiperazin-1-yl)methyl]aniline
4-(4-Methylpiperazin-1-ylmethyl)phenylamine is an intermediate used to prepare aminopyridopyrimidinones as tyrosine kinase inhibitors and anticancer agents. It is also used in the synthesis of piperazinyltrifluoromethylphenylquinolinylbenzonaphthyridinone derivatives with anticancer activities.
Properties of 4-[(4-Methylpiperazin-1-yl)methyl]aniline
| Melting point: | 97-99oC |
| Boiling point: | 331.2±27.0 °C(Predicted) |
| Density | 1.085±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 7.65±0.10(Predicted) |
| color | Yellow |
Safety information for 4-[(4-Methylpiperazin-1-yl)methyl]aniline
| Signal word | Warning |
| Pictogram(s) |
![]() Flame Flammables GHS02 |
| GHS Hazard Statements |
H226:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for 4-[(4-Methylpiperazin-1-yl)methyl]aniline
New Products
Cis-Tosylate Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 2,6-Dipicolic Acid 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Dibenzo[b,f][1,4]thiazepin-11(10H)-one N-BOC-piperidine-4-carboxylic acid 1-Benzhydrylazetane-3-carbonitrile AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2-(2-Chlorophenyl)glycine (±)-amino(2-fluorophenyl)acetic acid 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione MEHYL AMINE-D3.HCL METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O DEUTERIUM OXIDE FOR NMR TOLUENE-D3 BENZENE-D6 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran

![4-[(4-Methylpiperazin-1-yl)methyl]aniline](https://img.chemicalbook.in/CAS/GIF/70261-82-4.gif)
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SULFONYL]METHYL)-4-NITROPHENYL)METHANONE](https://img.chemicalbook.in/StructureFile/ChemBookStructure3/GIF/CB2235268.gif)



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