4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid
Synonym(s):4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid
- CAS NO.：1181226-02-7
- Empirical Formula: C14H11Cl2NO4
- Molecular Weight: 328.15
- MDL number: MFCD20527326
- Update Date: 2026-05-28 05:34:15
What is 4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid?
Biochem/physiol Actions
ZL006 inhibits the ischemia-induced interaction of nNOS with postsynaptic density protein-95 (PSD-95), preventing glutamate-induced excitotoxicity and cerebral ischemic damage. It does not inhibit nNOS itself. ZL006 is brain penetrant, and has been tested in both rat and mouse models of stroke.
Properties of 4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid
| Boiling point: | 530.4±50.0 °C(Predicted) |
| Density | 1.617±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: ≥5mg/mL (warmed to 60° C) |
| pka | 3.40±0.10(Predicted) |
| form | powder |
| color | white to tan |
Safety information for 4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid
New Products
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